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Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
02-04-2020, 05:42 AM
Post: #1
Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov
Yu Zhao, Zixian Zhao, Yujia Wang, Yueqing Zhou, Yu Ma, Wei Zuo

A novel coronavirus (2019-nCov) was identified in Wuhan, Hubei Province, China in December of 2019. This new coronavirus has resulted in thousands of cases of lethal disease in China, with additional patients being identified in a rapidly growing number internationally. 2019-nCov was reported to share the same receptor, Angiotensin-converting enzyme 2 (ACE2), with SARS-Cov. Here based on the public database and the state-of-the-art single-cell RNA-Seq technique, we analyzed the ACE2 RNA expression profile in the normal human lungs. The result indicates that the ACE2 virus receptor expression is concentrated in a small population of type II alveolar cells (AT2). Surprisingly, we found that this population of ACE2-expressing AT2 also highly expressed many other genes that positively regulating viral reproduction and transmission. A comparison between eight individual samples demonstrated that the Asian male one has an extremely large number of ACE2-expressing cells in the lung. This study provides a biological background for the epidemic investigation of the 2019-nCov infection disease, and could be informative for future anti-ACE2 therapeutic strategy development.


We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.

We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.

We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.

We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.

We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.
We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.
We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.

We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.
We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area.

https://www.biorxiv.org/content/10.1101/...985v1.full

Those who know, know! Big Grin
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02-04-2020, 06:03 AM
Post: #2
RE: Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
this study says that the virus primarily targets asian people!!!!

WOW

BOMBSHELL IF TRUE!!
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02-04-2020, 06:16 AM
Post: #3
RE: Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
another scientific paper:

Logistical and technical analysis of the origins of the Wuhan Coronavirus (2019-nCoV)

https://harvardtothebighouse.com/2020/01...2019-ncov/



--

i'm liking all these non-establishment PUBLISHING HOUSES or just SCIENTISTS who are directly posting to nontraditional FORMATS!!!

YES!
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02-04-2020, 06:16 AM
Post: #4
RE: Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
Quote: It considers whether the Wuhan Coronavirus (2019-nCoV) is the result of naturally emergent mutations against the possibility that it may be a bio-engineered strain meant for defensive immunotherapy protocols that was released into the public, most likely by accident since China’s rate of occupational accidents is about ten-times higher than America’s, and some twenty-times more than Europe’s – the only other regions with high-level virology labs.

this is what I'm thinking..

or it could be a SPY within the p4 lab that leaked it on PURPOSE working on behalf of NEFARIOUS AGENTS
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02-04-2020, 09:34 AM
Post: #5
RE: Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
(02-04-2020 06:03 AM)pug-thug Wrote:  this study says that the virus primarily targets asian people!!!!

WOW

BOMBSHELL IF TRUE!!

If true, I'm sure it's just a coincidence.

Pug, why are you ALWAYS race-baiting and seeing a racial aspect where non exists?

That makes YOU the RACIST!

/sarcasm off
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02-04-2020, 09:52 AM
Post: #6
RE: Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
something doesn't smell right about this..

lack of transparency to the max.

hard to tell who benefits from this.

i can see that protests may be stopped by stuff like this, but at the cost of the economy

I can see how the west can benefit from this by isolating China into a corner.
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02-04-2020, 11:17 AM
Post: #7
RE: Single-cell RNA expression of ACE2, the putative receptor of Wuhan 2019-nCov
(02-04-2020 09:34 AM)Dick Tater Wrote:  
(02-04-2020 06:03 AM)pug-thug Wrote:  this study says that the virus primarily targets asian people!!!!

WOW

BOMBSHELL IF TRUE!!

If true, I'm sure it's just a coincidence.

Pug, why are you ALWAYS race-baiting and seeing a racial aspect where non exists?

That makes YOU the RACIST!

/sarcasm off

Pump the brakes here, Dick. Are you saying that races differ from one another, on the biological level?
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